Studies on cell compression involve subjecting biological cells to mechanical forces that result in the cell’s shape or structure deformation.

These studies are essential for understanding how cells respond to mechanical stress, which has implications for various physiological processes, tissue engineering, and disease research. 

The effects of cell compression occur on a multiscale level. While standard optical microscopy can efficiently reveal cellular processes on the microscale, capturing the nanoscale events more precisely is essential for fully understanding cellular response to compressive stress.  

Abbelight systems enable super-resolution imaging of large samples. The largest field of view on the market, achievable thanks to the ASTER illumination technology, allows imaging of many mammalian cells within one acquisition. Imaging of large cellular structures, such as actin or microtubule cytoskeleton in super-resolution, is optimized by Abbelight’s specialists. Abbelight Blinking Pad can be used for studies on non-adherent cells. Abbelight NEO software provides on-the-fly reconstruction and drift correction to directly see the results and assess the sample quality.