Trypanosoma brucei

Jamin Jung
Trypanosome Cell Biology - Department of parasites and insect vectors

 

Trypanosoma brucei fixed with methanol and stained with primary anti ITF172 antibody and secondary coupled to AlexaFluor647

3D-dStorm using DONALD technology

Segmentation and clustering (DBSCAN)

The study aims to unravel the molecular bases for the role of Intraflagellar Transport (IFT) 172 in ciliogenesis and in ciliopathy; Trypanosoma brucei, a monocellular parasite, is used as model organism, because of its well-developed flagellum with evolutionarily conserved functional modules.